Professor Rick Titball
Rick Titball is Professor of Molecular Microbiology at the University of Exeter. He moved to the University of Exeter from the Defence Science and Technology Laboratory (Dstl) at Porton Down in 2007, where he was a Senior Fellow. He has worked on bacterial pathogens of humans and animals including Burkholderia pseudomallei, Yersinia pestis and Clostridium perfringens and developed vaccines against plague and C. perfringens toxins which are now being exploited by industry. His work at Exeter is directed towards understanding the molecular basis of virulence of B. pseudomallei and C. perfringens and the molecular biology of toxin-antitoxin systems. At Exeter an underpinning feature of his research has been the use of alternative infection models, including G. mellonella larvae, to study disease. He has published over 300 peer reviewed papers including work in Nature, Science and PNAS. He has 18 currently active patents. In 2015 he co-founded Biosystems Technology, a company developing alternatives to mammals for biological research development and testing. His work has been funded by the UK Dstl, BBSRC, MRC and Wellcome Trust, Innovate UK and NC3Rs and internationally by the Cariplo Foundation, US NiH and US DTRA.